In summary, the reproducibility of 6MWT and 30sec-STS was excellent in patients with severe and very severe COPD. Unlike previous studies, we did not find a learning effect by following the standardized guidelines. Compared to the T1 results, there was a significant average improvement of 7.9 m in 6MWD on T2, which was performed 7-10 days apart and evaluated by different advisors. We consider this difference to be small and of no clinical relevance, whereas the 20.5 m SEM was acceptable and lower than the MID established for 6MWT. The reproducibility of cardiorespiratory variables (saturation, HR and perceived dyspnea) was good and acceptable. Based on our results, repeated 6MWT and 30sec-STS can be performed by different clinical practice advisors, and a 6MWT and 30sec-STS may be sufficient to evaluate patients with severe and very severe COPD. However, the responsiveness of 30sec-STS will need to be studied in future studies. The main result was an expert judgment on total patient toilets for alternative work (IFAP 3b), which was used by insurers to calculate patients` profits. Secondary outcomes were toilets for last patient work (IFAP 3a), safety of experts in their own wc assessments (scale 0-10), perceived patient equity during evaluation (a 29-point questionnaire [20, 21], see additional file 3), including overall satisfaction with the evaluation (scale 0-10) and evaluation of functional assessment by experts (telephone interviews , RELY 1; Online survey, RELY 2). Bodilsen AC, Juul-Larsen HG, Petersen J, Beyer N, Andersen O, Bandholm T. The feasibility and reliability of physical performance measures in elderly patients with acute authorization. PLoS One. 2015;10 (2):e0118248.
The main results of the 30sec-STS were excellent reliability and acceptable matching. The average improvement of 0.6 recurrences of T1 to T2 was small and most likely of low clinical importance if the goal is to measure a treatment effect. Our reliability and compliance results in patients with severe and very severe COPD were identical to those reported in other patients with kidney disorders (ICC 0.93). SEM: 0.9; DTH: 2.6),47 type 2 diabetes (CCI 0.92; SEM: 1.2; DTH: 3.3),33 hip osteoarthritis (ICC 0.88; SEM: 1.5; DTH: 3.5),31 acute illnesses (CCI 0.82; SEM: 1.32; DTH: 3.7),48 Hip Replacement (ICC 0.88; SEM: 1.0; DTH: 2.8.30 cognitive impairment (CCI 0.94; SEM: 0.9; DTH: 2.4),49 and stroke in hospital (ICC 0.87; SEM: 1.0; DTH: 3.0.50 The original research plan proposed an assurance study on functional assessment and wc judgments (RELY 1), followed by a randomized comparison with current practice . Since rely 1 government changes have stalled for more than a year, the observed reproducibility reflects the effects of short training in functional assessment without standardization . The reproducibility of untrained experts may be relatively low or worse. To test whether psychiatrists consistently differ in their assessments, we formulated two mixed effect models. The zero model consists of a percentage WC as a response variable, an intercept as a single fixed effect and a random intercept for applicants. The alternative model includes random cross-interceptors for complainants and psychiatrists.